Compare FDA-approved weight loss medications including GLP-1 agonists, appetite suppressants, and more. Find options that fit your health goals and budget.
Click any medication to view full details, pricing, side effects, and comparisons.
Generic: semaglutide
Type 2 diabetes
Generic: semaglutide
Weight loss
Generic: tirzepatide
Weight loss • Obesity
Weight loss • Obesity
Type 2 diabetes • Weight loss
Type 2 diabetes • Weight loss
Type 2 diabetes • Weight loss
Generic: tirzepatide
Type 2 diabetes • Weight loss
See which medication is right for you with our side-by-side comparison tool.
Compare Two Drugs →GLP-1 agonists like Wegovy (semaglutide) and Zepbound (tirzepatide) have shown the highest weight loss results in clinical trials, with patients losing 15-22% of body weight.
Both contain semaglutide, but Wegovy is FDA-approved specifically for weight loss at a higher dose, while Ozempic is approved for type 2 diabetes.
Coverage varies widely. Many insurers cover diabetes medications like Ozempic but not weight-loss-specific drugs like Wegovy. Check with your insurer and ask your doctor about alternatives.