About Ozempic
Ozempic (semaglutide) is a once-weekly injectable prescription medication manufactured by Novo Nordisk. It belongs to the GLP-1 receptor agonist class and was FDA-approved in 2017 for improving blood sugar control in adults with type 2 diabetes, alongside diet and exercise. In 2021, the FDA also approved it to reduce the risk of major cardiovascular events — such as heart attack and stroke — in adults with type 2 diabetes and established cardiovascular disease. Ozempic has gained widespread recognition due to its notable weight loss side effect, which led to the development of Wegovy (a higher-dose semaglutide) specifically for obesity treatment.
How It Works
Ozempic mimics the GLP-1 hormone that is naturally released after eating. It stimulates the pancreas to release insulin when blood sugar is high, suppresses glucagon (which raises blood sugar), slows the rate at which food leaves the stomach (gastric emptying), and signals the brain to reduce appetite. Together, these effects lower blood sugar levels and contribute to weight loss.
Key Facts
- ✓Once-weekly subcutaneous injection — same day each week
- ✓Starting dose: 0.25 mg/week for 4 weeks, then 0.5 mg/week
- ✓Maximum dose: 2 mg/week
- ✓Average A1C reduction: 1.5-2.0 percentage points
- ✓Average weight loss: 6-8% of body weight
- ✓Pen injected into abdomen, thigh, or upper arm
Who Is Ozempic For?
Ozempic is prescribed for adults with type 2 diabetes who need better blood sugar control, particularly those who also have cardiovascular disease or risk factors. It is not for type 1 diabetes. It may be used alone or with other diabetes medications like metformin. People who have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use Ozempic.
Snapshot
Cost
Estimated monthly cost:
Medical Disclaimer: This information is for educational purposes only and should not be used as a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Prices shown are estimates and may vary by location and pharmacy.