About Escitalopram
Escitalopram, sold under the brand name Lexapro, is a selective serotonin reuptake inhibitor (SSRI) widely prescribed for major depressive disorder (MDD) and generalized anxiety disorder (GAD). It is the S-enantiomer of citalopram (Celexa) and is considered the most selective SSRI available, meaning it acts very specifically on the serotonin transporter with minimal off-target effects. This selectivity is associated with fewer drug interactions and good tolerability. Available as a generic, it is considered one of the top first-line treatments for depression and anxiety in multiple clinical guidelines.
How It Works
Like other SSRIs, escitalopram blocks the serotonin reuptake transporter (SERT), increasing the amount of serotonin available in synaptic gaps between neurons. Its high selectivity for SERT means it has minimal effects on other receptors, contributing to its favorable side effect profile compared to older antidepressants and even some other SSRIs.
Key Facts
- ✓FDA-approved for depression and generalized anxiety disorder
- ✓Considered most selective SSRI — fewer drug interactions
- ✓Available as affordable generic escitalopram
- ✓Once-daily dosing: 10-20 mg
- ✓Typically takes 2-4 weeks for initial effects, 4-8 weeks for full benefit
- ✓Avoid abrupt discontinuation — taper under medical supervision
Who Is Escitalopram For?
Escitalopram is prescribed for adults and adolescents (12+) with major depressive disorder, and adults with generalized anxiety disorder. Its clean drug interaction profile makes it a preferred choice for elderly patients or those taking multiple medications. It is not appropriate for people currently taking MAOIs or with a QT prolongation history at higher doses.
Snapshot
Generic name
escitalopram
Drug class
SSRI
Category
depression
Forms Available
tablet, capsule
Cost
Estimated monthly cost:
$$$$ Brand
$$ Generic
Related Medications
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Medical Disclaimer: This information is for educational purposes only and should not be used as a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Prices shown are estimates and may vary by location and pharmacy.